Whatever Happened to Baby Gin? is the 22nd episode of the eighth season, and 184th overall. It is the penultimate episode of the series.
Just as Grace and Will are settling into the idea of raising the baby together, Will's boyfriend Vince surprises him with an announcement that will lead Will to choose between his commitment to Grace and his relationship with Vince. Meanwhile, Karen shocks everyone when she announces that she has a sister, Gin, who was injured as a child during a game of Twister. Josh Lucas, on the other hand, comforts Jack after a devastating discovery when his new show "The Badge" premieres.
- Eric McCormack (Will Truman)
- Debra Messing (Grace Adler)
- Sean Hayes (Jack McFarland)
- Megan Mullally (Karen Walker)
- Shelley Morrison (Rosario Salazar)
- Bobby Cannavale (Vince D'Angelo)
- Bernadette Peters (Gin)
- Josh Lucas (Himself)
- Charles C. Stevenson (Smitty)
- The storyline with Karen and Gin draws heavy parallels with What Ever Happened to Baby Jane?, after which the episode is named. (episodes referencing movies rarely have anything to do with the movie itself)
- Gin suggests to Karen ordering a pizza and watching Family Guy. Episode writer Gary Janetti was a producer for the show from 1999-2016.